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According to MRFR analysis, the global nanobody market size is expected to register a CAGR of 24.2% from 2022 to 2030 and hold a value of over USD 1.14 billion by 2030
The global market of nanobody is driven by various factors, such as rising healthcare expenditure and increasing investments in R&D activities to develop nanobody-based therapeutics. In addition, the growing usage of nanobodies in various applications such as in vivo imaging, antivenom therapy, and immune-based therapeutics among others is also driving the market growth of the nanobody. Moreover, the progress of various nanobody products in clinical trials and their subsequent approval further boost the growth of the market. Furthermore, rising health-related concerns coupled with favorable reimbursement policies for availing healthcare services are anticipated to fuel the growth of the nanobody market during the forecast period.
The industry players are also focusing on new product development and obtaining product approvals from regulatory bodies for increasing their penetration in the global nanobody market. For instance, in March 2021, Taisho Pharmaceutical Co., Ltd. (Japan), announced the pplication submissiom rearding rhe approval of manufacturing and marketing the Anti-TNFα Multivalent Nanobody Compound (Ozoralizumab) in Japan for the treatment of rheumatoid arthritis. Furthermore, the key players are involved in strategic agreements and collaborations to develop novel nanobody-based medications and augment their market positions. For instance, in February 2021, i2O Therapeutics, Inc. (US) announced a research collaboration with Sanofi S.A. (France) to investigate oral delivery of nanobody-based medicines for the treatment of a range of serious and life-threatening diseases such as oncology and rare diseases among others.
Nanobody Market Insights, Analysis and Forecast by Type (Mono-specific and Multi-specific), by Application (Therapeutic [Cancer, Neurodegenerative Diseases, Infectious Diseases, and others], Diagnostic [Detection of Proteins and Microorganisms, Detection of Small Molecules, and Imaging], and Research), by End User (Pharmaceutical & Biotechnology Companies, Research Laboratories, and Others), and by Region (North America, Europe, Asia-Pacific, and Rest of the World)—Forecast to 2030
Major Key Players:
Some of the key nanobody market players are Sanofi S.A. (France), Merck KGaA (Germany), Alphamab Oncology (China), Bristol Myers Squibb (US), Novartis AG (Switzerland), GenScript Biotech Corporation (US), Sensei Biotherapeutics (US), Beroni Group (Australia), DiosCURE Therapeutics SE (Germany), ExeVir Bio BV (Belgium), and Taisho Pharmaceutical Holdings Co., Ltd. (Japan).
Segment Analysis
The global nanobody market has been segmented into type, application, and end user.
Based on type, the market has been segmented into mono-specific and multi-specific. The mono-specific segment held a larger market share in 2021. The mono-specific nanobody available in the market incuded Cablivi (Caplacizumab) marketed by Sanofi S.A. (France). In addition, many pharmaceutical organizations are investing in R&D for the discovery and development of novel multi-specific nanobody drug candidates. Thus, many multi-specific nanobody drug candidates are in various phases of clinical trials for the treatment of cancer and other chronic diseases.
Based on application, the market has been segmented into therapeutic, diagnostic, and research.
The therapeutic segment is further segmented into cancer, neurodegenerative diseases, infectious diseases, and others. The diagnostic segment is further segmented into the detection of proteins and microorganisms, detection of small molecules, and imaging.
Based on end user, the market has been segmented into pharmaceutical & biotechnology companies, research laboratories, and others. The pharmaceutical & biotechnology companies segment held the highest share in 2021, due to the rising investment in R&D activities for the development of nanobody-based new therapeutics for the treatment of chronic disorders such as neurodegenerative diseases, rheumatoid arthritis, osteoporosis, and other conditions.
Regional Analysis
North America is likely to dominate the nanobody market, owing to increasing investments in R&D by the key players & research institutes coupled with well developed healthcare infrastructure in the region. Furthermore, the presence of major industry players across the region, such as Thermo Fisher Scientific Inc. (US), Sensei Biotherapeutics, Inc. (US), Cusabio Technology LLC (US), and other players are further contributing to the regional growth.
Europe is likely to account for a significant share of the nanobody market due to the presence of a well-developed healthcare infrastructure and high healthcare expenditure. For instance, according to the Eurostat database, healthcare expenditure was 8.0% of GDP in 2020. Moreover, the rising product approvals from regulatory bodies is also expected to drive the growth of the global nanobody market in Europe during the forecast period. For instance, in September 2018, Cablivi (Caplacizumab) was granted marketing authorization by the European Commission for the treatment of Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in adults.
Asia-Pacific is projected to be the fastest-growing regional market during the forecast period due to factors like improved healthcare infrastructure and a high percentage of the geriatric population in the region demanding efficient therapeutics. Furthermore, initiatives undertaken by key players to expand operations in the region are also boosting the market growth.
Furthermore, the growth of the market in the Rest of the World is slower compared to the other regions due to the limited healthcare infrastructure and fewer research activities. However, increasing government initiatives for improving the healthcare sector and the rising prevalence of cancer and other chronic diseases are expected to drive the market over the forecast period.
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