Malegra DXT is a popular medication prescribed to treat two common sexual health issues in men: erectile dysfunction (ED) and premature ejaculation (PE). It combines two active ingredients—Sildenafil (commonly used for ED) and Duloxetine (used for PE). While Malegra DXT can be highly effective on its own, many men wonder whether it requires lifestyle changes to work at its best. • Sildenafil (for ED) works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which normally breaks down cGMP, a substance responsible for relaxing blood vessels in the penis. By blocking PDE5, Sildenafil helps increase blood flow to the penis during sexual arousal, leading to an erection.
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