The key to Filitra’s effectiveness lies in its ability to enhance blood flow through the inhibition of the enzyme phosphodiesterase-5 (PDE5). PDE5 is an enzyme found primarily in the smooth muscles of blood vessels, including those in the penis. Under normal circumstances, PDE5 works to break down cyclic guanosine monophosphate (cGMP), a substance responsible for relaxing the smooth muscles and dilating blood vessels.
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