He did his undergraduate work at The Pennsylvania State University in 1994 and attended medical school at the Philadelphia College of Osteopathic Medicine, graduating valedictorian in 1989. He continued his training at the Chicago Osteopathic Medical Center in Orthopedic Surgery from 1989 to 2004 and entered in private practice, focusing on general orthopedics, with an interest in adult reconstruction and sports medicine.
In 2002, when a representative from one of the major joint replacement companies brought a centrifuge into the operating room, his love for regenerative medicine and PRP began. In 2009, he switched from a surgical practice to one focusing on the regeneration of tissue, not replacement, and his mindset on medicine began to evolve. As his protocols, and products evolved, Dr. Piccirillo began consulting with other practices, teaching them how to get on the regenerative medicine platform. He recently completed his book, Perfect PRP™, which covers his trademarked method for getting the most from a patient’s PRP.